Services

Institut National de Recherche pour l'Agriculture, l'Alimentation et l’Environnement (INRAE)-IERP is dedicated to fish infectiology. It supports research programs on fish pathology, immunology, vaccinology, and genetics of resistance/susceptibility to diseases.

EOPS rainbow trout and carp are available for infectious challenges. Trout are the INRAE reference strain or from isogenic lines with contrasted resistance to a range of pathogens produced at INRAE-PEIMA (collaboration agreement). IERP also has access to inbred carp families from WU.

The fish installation (1000m²) consists in rooms for breeding pathogen-free fish with 4 RAS, 344 incubators or 86 aquaria, 18 tanks of 200L. The infectiology part (BSL2 confinement) has 104 aquariums in recycled or flow-through water, 14 tanks of 300L in recycling or in lost water. Imaging equipment enables fish monitoring and host-pathogens interactions through GMO pathogens with reporters.

INRAE-IERP produces and supplies rainbow trout and carp with specific genetic and sanitary status, and performs in vivo infectiology experiments. Pathogens include both classical and emerging viruses and bacteria (trout: VHSV, IHNV, ISAV, Alpha virus SDV and SPDV, Flavobacterium psychrophilum; carp: SVCV). Experimental set-up benefits from the expertise of INRAE labs Molecular Virology and Immunology (VIM) and Animal Genetics and Integrative Biology (GABI).

INRAE-IERP also comprises an imaging platform (clearing; biphotonic microscopy ...) in which new protocols are developed, including the usage of fluorescent pathogens to better monitor infections. The facility is part of the EMERG’IN research infrastructure and is also a partner of the VetBioNet infrastructure project.

Support offered

In addition to the above information, technical support for daily experimental work and technical help for samplings will be provided to all users. For specific needs, INRAE scientists using the infrastructures (genetics, nutrition, physiology, pathology) will assist users for experimental design and data interpretation.

Modality of access

Each user is expected to stay 5 days at the infrastructure (2.5 days at the beginning and 2.5 days at the end).