Fish experimental facilities and associated lab (dissection), and fully equipped laboratory for cell and molecular biology, including GMO (DTU aqua AAH) The fish experimental facility at DTU AQUA, unit of fish and shellfish diseases comprises approx. 120 experimental tanks of various sizes (5, 180, 500 and 1000 litres). The experimental tank facilities can operate at various temperatures and salinities and both flow-through and recirculation systems can be made available in the tanks. It is also possible to carry out trials with different concentrations of CO2 diluted in water. This guarantees that well-controlled trials can be conducted with a wide range of fish pathogens on most freshwater and saltwater fish and crustacean species. The infrastructure includes:

- A Pathogen Free (SPF) Hatchery for supply of experimental fish, this unit is fully recirculated and is supplied only with softened freshwater.

- A quarantine unit, which can be supplied with both fresh and saltwater, where it is possible to house a variety of fish and crustacean species (e.g. seabass, lumpfish, salmonids, shrimps) and where it is possible to conduct vaccination trials and trials with non-infectious reagents

- A highly contained experimental unit capable of housing challenge trials with all known fish pathogens (including notifiable infectious agents) and bioengineered organisms (GMO) under both fresh- and saltwater conditions. All water used in the highly contained unit is pasteurized before discharge, enabling us to conduct experiments with exotic and highly infectious pathogens.

- A fully equipped dissection laboratory for sample preparation is included in the experimental tank facilities.

Infectious disease laboratory and fish cell bank. State-of-the-art laboratories for cell and molecular biology (Biosecurity level 2) are part of the infrastructure. These include a virology and bacteriology lab for propagation and in vitro immunochemical characterization of the pathogens, and a molecular laboratory for PCR and sequencing. A GMO laboratory is available, along with access to Fluidigm, next-generation sequencing and Matrix-assisted laser desorption/ionization Maldi-Tof. Access to laboratories is guaranteed for the processing of samples from the different TAs. The Unit for Fish and Shellfish Diseases at DTU Aqua is being operated as accredited according to ISO 17025 and it hosts the European Union Reference Laboratory for Fish and Crustaceans Diseases and the OIE Reference Laboratory for VHS and is leading within research and diagnostics on Infectious fish diseases. The service team has in-depth experience in the handling, management, and care of fish and crustaceans at all stages.